ACME
ACME HPLC/UHPLC columns are based on a new 120 Å ultra-high purity (99.999%) extra-treated porous spherical silica with a narrow particle size distribution and an extremely low metal content(< 10 ppm) to minimize silanol acidity and reduce surface metal sites available for chelation. ACME PLUS HPLC/UHPLC are based on the same ultra-high purity silica with a pore size of 200 Å.
Combined with a proprietary bonding technology this results in columns with optimal efficiency, asymmetry, and minimal back pressure. ACME silica pore structure shows dramatically improved performance on real samples.

- Ultrapure porous silica particles enable high peak efficiency across all particle sizes.
- 1.9, 3, 5 µm particle sizes for simple method transfer between HPLC & UHPLC.
- Column hardware compatible with HPLC and UHPLC.
- Consistent and reproducible retention times allowing direct scale-up from the laboratory through process applications.
ACME C18 | ACME C8 | ACME CN* | ACME Ph | ACME PLUS | ACME PAH | |
---|---|---|---|---|---|---|
Bonded Phase | -C18H37 | -C8H17 | -R-CN | -R-C6H5 | -C18H37 | -(C18H37)x |
Separation Mode | Reversed-Phase | |||||
Base Material | Ultrapure Extra-Treated Porous Spherical Silica | |||||
Purity (%) | 99.999, metals < 10 ppm | |||||
Surface Area | 260 m2/g | 200 m2/g | ||||
Particle Size (s) | 1.9 µm, 3 µm, 5 µm | |||||
Pore Size | 120 Å | 200 Å | ||||
Carbon Load (%) | 16 | 10 | 7 | 10 | 12 | 17 |
Endcapping | Yes Proprietary | Yes Proprietary | Yes Proprietary | Yes Proprietary | Yes Proprietary | No |
pH Range | 1.8 to 9.5 | 1.8 to 9.5 | 2 to 7.5 | 1.8 to 9.5 | 1.8 to 9.5 | 1.8 to 9.5 |
Temperature Limit | 60 °C | 60 °C | 50 °C | 60 °C | 60 °C | 60 °C |
Aqueous Compatibility | ≤ 98% | ≤ 98% | 100% | 100% | ≤ 98% | ≤ 98% |
USP Listing | L1 | L7 | L10 | L11 | L1 | L1 |